Diablo Crossover.

The Archangel of Justice destroyed the Worldstone to spare Humanity the corruption Baal infected it with. The force of its death knell shatters Mount Arreat and sends Tyrael hurtling across the endless planes of reality. He falls upon a world untouched by Angel or Demon, far from the sight of the High Heavens. So far, in fact, that he fears he will not be reborn from the Crystal Arch.

Wounded and near death, hope appears in the form of two strange creatures bearing the power of night and day.

Tyrael now faces a time of recovery as his power slowly heals within a body fashioned for him by his saviours. Justice Incarnate tastes for the first time the life of a mortal, and it is a strange, confusing experience .He has been left in the care of one Twilight Sparkle to learn of this world.

After all, where better to find peace and harmony than Ponyville?

Act I - The Root of Evil
Act II - ????????
Act III - ???????
Act IV - ???????

[Cover image used with full permission of the owner. Go on, go have a look at Chagial's stuff.]

A human wakes up in the everfree before the events of nightmare moon. Or adult Luna and Celestia. Oh, and he’s a bird. A magical bird, but still a bird.

When Jason and his fellow developers are tasked with working on their game’s latest expansion, they find themselves on a death march to get it completed before the deadline. Jason takes on a three-day shift to test certain aspects of the expansion pack. Only when he finally passes out from the exhaustion... he wakes up in the body of his test character! Left in the bright land of Equestria as Blackjack, he must figure out his powers and maybe even a way back home.
This new death march will test his abilities to interact with the Equestrians, for better or worse.

After years of being the runt of the litter (despite having no siblings), Spike finally comes into his own and starts to grow up and mature. The result is a unique bit of magic all his own, or so the theory goes: He awakens one morning to find words hanging overhead that call him [The Gamer], along with powers that let him 'live life as though it were a game'.

How he decides to handle all of this, and where things go from there? That would be a spoiler, and you all know how we feel about spoilers around here...

Frequently asked questions will be answered from time to time, and those answers linked here for the curious:
The First FAQ

After losing her hive, Queen Chrysalis is forced to start another one. Luckily she has the help of a few loyal subjects who never accepted their fellow changelings new way of life. They must stay hidden from enemies, collect enough food to survive and rebuild their strength. Now the first brood has hatched and there is something very different about one of the larva.