The instant she appears in this world, things go wrong for Twilight Sparkle. Fortunately, Anon the veterinarian is there to save her, and during the recovery process, they find they quite enjoy each other's company. Eventually Twilight wants to make her way back home and Anon has a decision to make.
Meanwhile Celestia, thinking Twilight is in danger, ventures to earth to rescue her, only to encounter dangers of her own. Princess Luna has to figure out how to rescue both of them without abandoning Equestrian rule.