It is the year 2038, and the Earth is slowly being consumed by a space-borne monstrosity dubbed the Black Tide, which is using nanotechnology to remake the planet into something hideously alien.

Erin Olsen works for Project Harmonics, humanity's last-ditch effort to find a new world before the Tide can wipe them out. But when that world is found, and it turns out to be occupied, Erin will need to find the courage to face the unknown in order to save the inhabitants of both worlds.

(Many thanks to Easteu for the fantastic cover image for this story!)

Now with its own TV Tropes page

There is now a follow-up to this story: Sunflower - Side Projects
Sequel: Project Sunflower: Harmony

Twilight Sparkle wakes up one morning to a harsh dose of unreality. She is stranded, without her friends, on an island which matches no known locale on Equestria. Surrounded and harried on all sides by the alien and the dangerous, she will find her mettle sorely tested, and find perhaps that the best friends you will ever have in your life are the ones you make when your back is to the wall...

Thanks to CedricBale and noobie56xx for tracking down the name of the artist so I could give them credit.

Twilight gets drunk and ships Rainbow Dash with everything in the universe.

Rainbow Dash is not amused.

Diablo Crossover.

The Archangel of Justice destroyed the Worldstone to spare Humanity the corruption Baal infected it with. The force of its death knell shatters Mount Arreat and sends Tyrael hurtling across the endless planes of reality. He falls upon a world untouched by Angel or Demon, far from the sight of the High Heavens. So far, in fact, that he fears he will not be reborn from the Crystal Arch.

Wounded and near death, hope appears in the form of two strange creatures bearing the power of night and day.

Tyrael now faces a time of recovery as his power slowly heals within a body fashioned for him by his saviours. Justice Incarnate tastes for the first time the life of a mortal, and it is a strange, confusing experience .He has been left in the care of one Twilight Sparkle to learn of this world.

After all, where better to find peace and harmony than Ponyville?

Act I - The Root of Evil
Act II - ????????
Act III - ???????
Act IV - ???????

[Cover image used with full permission of the owner. Go on, go have a look at Chagial's stuff.]

A slightly more realistic take on the "Human in Equestria" story concept.

... For a given value of "realistic."

Okay, it's barely realistic but it is a hell of a lot of fun...

Now with an image graciously provided by Page Turner, and an audiobook version narrated by multifanficaday and if you prefer it in German, FrankyDoodle has got you covered!

And a TVTropes Page!

Last Featured: 11/26/2019! Thank you so much!

What if Nanoha never became the White Devil?

Twilight Sparkle, as everypony knows, is a magical pony by nature and profession. However, even she is confused when she encounters a mysterious ferret and an equally mysterious jewel. Forced into conflict by a monster attack, Twilight releases the power of the jewel, summoning the device known as Raising Heart.
Tasked with the retreival of a set of mysterious artifacts known as the Jewel Seeds, Twilight and her friends face an entirely new set of challenges. Unbeknownst to them, however, forces outside of Equestria are moving to claim the very same artifacts they now hunt.

A crossover with Magical Girl Lyrical Nanoha, with an equine twist!
---
A sequel has begun. Go Here For Magical Pony Lyrical Twilight A's

Magical Pony Lyrical Twilight by PurpleProse is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License.

It was such a small wish...

It's been nearly a year since the Jewel Seeds fell to Equestria and changed the lives of Twilight and her friends. The Time-Space Administratrion Bureau is officially opening talks with Equestria, and Twilight's new human friends are returning.

The joyous occasion is interrupted, however, by the appearance of a new threat; a set of mysterious mages armed with powerful Devices and daunting magical prowess. Who are these mysterious people that call themselves the Wolkenritter? Who do they serve?

Twilight and her friends, both old and new, are once more forced into conflict. This time, however, Equestria's future may very well hang in the balance.
---
This is a sequel to Magical Pony Lyrical Twilight. Please read that story before beginning this one. You can find the story here.

Magical Pony Lyrical Twilight by PurpleProse is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License.