There are two big philosophy’s on killing others if you’re a smart wastelander. Shoot, and aim to hit, or throw explosives and prey. Hard Brass has never been a real smart wastelander.
Disturbing lack of ponies taking use of their Creator-given limbs, Brass plans to fix that. If you can’t kill something else with your own four good legs, then you are unprepared.
Reload, fire, reaload, fire, throw. You’ll eventually run out. You run out, you don’t get to run away.
Then, when a pony charges at you, ready to take off your head with pure strength, what are you to do?
Run, fast as your legs can take you. But if you are some morally corrupt bandit, you will never run fast enough. You will be caught by the Sentinel.