A strange epidemic has struck Equestria. It causes Pegasi to rip off their wings and throw themselves to their deaths. It causes Unicorns to lose their magic and eat their own horns, and it causes Earth ponies to tear out their manes and tails and exhibit dementia like symptoms. It leads to death in all three species.

Mass suicides break out in Cloudsdale. Celestia heads to Cloudsdale only to return with the same symptoms. Luna then gets a letter from Twilight saying that the Earth ponies of Ponyville have started tearing out their manes and tails. A second letter comes from the new Unicorn colony that many of the Unicorns are losing their magic. Things go from bad to worse when Celestia loses her own magic leaving Luna to raise ans set the sun as well as the moon.

Luna brings Twilight, Zecora, Regalia the Griffin medic, Ramoth the dragon healer, and Zaphod the Minotaur doctor together in Canterlot to try to solve this mystery.

(Author's notes: Prions are real and all the medical stuff in this piece is all real too. A Prion is a protien that attacks the brain by destroying the neurons and causing strange behavior much like what we see in Dementia and in Alzheimer's. Feel free to give criticism and ask questions if you don't understand something. I'll be very happy to answer your questions to the best of my ability. A lot of research went into this. Enjoy! (No worries, no gore))

It has been three months since the assassination attempt of Shining Armor and Princess Cadance. Silent Wind has been much better ever since he's been with his Marefriend, Twilight Sparkle. But one day, he is called to The Kingdom of Canterlot to talk to Princess Celestia.

Little do they know, they have come on the right time to talk to The Leader of the Silentblades. For he comes to Canterlot for a certain Stallion, Silent Wind.

Old and New allies are made, Friends die, Old Friends are united and Old Enemies return.

What will be the fate of Equestria?

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Assassin's Tears I is Highly recommended to read first before this.

Assassin's Tears III is out, find it here.

“What have you done, Twilight?! What have you done?! You killed us all! You killed us all! You should be dead!”

After a message from a terrible future where ponies are killed by Twilight's hooves as a powerful tyrant including her friends, family and the Princesses, Twilight belives that there is one way to stop all this from happening. Her death.

However, after wakening up from her apparent death, she finds her self in a diffrent future, where ponies are not dying by her taking over but by the mistake of dying and not there save Equestria from everything else. Now, she must find out what has happened to creating this diffrent future. Are her friends all dead? What happened to Celestia? How did she live? And why can't she get back to her own time?

This series was supposed to be M rated but decided to lower it. M rated will be featured in a seperate series if requested.
Teen rated cause of light amounts of blood shed but it is mostly curse words, some violence and mild sexual sessions.

Twilight Sparkle has always been Princess Celestia's perfect student. A model of good behavior, of friendship, and most importantly, raw magical skill.

But what if that magical skill wasn't accidental?

What if Twilight was just a weapon?

And what happens if she finds out?

A very, very special thanks to Ralastas (http://www.fimfiction.net/user/Ralastas) for assisting me in this and writing Twilight's final letter.

If Celestia is God, then who are her Angels? Based on Cupcakes by Sgt. Sprinkles: In the aftermath that follows the tragedy at Sugarcube Corner, the Elements of Harmony are lost and broken. However, one night, Luna visits Twilight's dreams to inform her of a powerful resurrection spell. When Dash returns, she isn't the pony that her friends remember and what's more, an 'angel' has followed her into the living realm.

When your life is as dull a gray as the world that surrounds you, the mundanities can make it all seem meaningless. Sometimes all we need is a little color -- or six -- to reintroduce us to what truly makes life worth living.

*6-16-2017 Edit, added Rainbow Dash tag because it triggered knighty.*

When Princess Celestia makes an unthinkable choice to continue on as the ruler of her people, she is forced to confront the most painful question she has ever asked herself: What will her most faithful student think of the monster she has become?

On a dark night filled with even darker magics, an insane cult attempts to give Nightmare Moon a body and life of her own, utterly separate from Princess Luna. But, when the spell is interrupted by Celestia, something unexpected is created.

Now, a little black alicorn filly named Nyx finds herself living under the care of Twilight Sparkle, only to be haunted by memories and emotions from her past. Is she Nightmare Moon reborn or is she simply a doppelganger with a soul and mind of her own? Can Twilight Sparkle protect Nyx from those who refuse to see past her dragon eyes and black coat?

Or, will Nyx be forced to inherit the sins that may not even be hers and become the greatest evil Equestria has ever known?

Each night I’m trapped in the dark, immobilized. I hear whispers as they operate on me: they say I shouldn’t be alive. Twilight refuses to tell me about the operation. Sometimes she can’t look me in the eye. What did they do to me?

Nothing used to scare me: I kicked a dragon in the nose, defeated gods of chaos and hatred, and control the weather. Now I feel broken. My memories have shattered, I feel wrong, and I’m afraid to tell anypony how scared I am.

I can’t even do the rainboom anymore. Who am I? I’m no longer the best flyer in Equestria, yet everypony assures me I am. Why won’t they tell me the truth?
↓↓ Credits

Special Thanks:
Dreampaw the artist. Best cover art.
Editors:
ArgonMatrix - Fixed 128 errors in chapter one alone.
Animus - who is awesome and for hire.
BronyWriter - The only author to punch Celestia in the face, and live.
Jaestring - Artist, Editor, and Female all in one.
Abcron - European editor, which means his time zone and my actual sleep schedule are aligned perfectly!
The Parasprite. Need I say more?
Selbi - If your editor isn't German, you aren't trying hard enough.
OctaviaHarmony - His avatar is as sexy as his editing.
RenegadeTimelord - Doctor who?
Akumokagetsu - Awesomesauce.
(Wow, a lot of editors came and went.)

What if Twilight was orphaned before her acceptance into Celestia's school for gifted unicorns?
what if she and the princess of the sun became inseparable? What if Twilight starts calling Celestia mommy after their lessons?
What if Celestia loves it?
Inspired by the cover photo