Rainbow Dash finds a maimed, unconscious young colt on the edge of Ponyville and rushes him to the hospital, but nopony knows who he is and something about him seems off...
A human soul is stuffed into King Sombra's body. Having no idea what's going on, and thinking he is in some kind of coma, he just casually strolls into the Crystal Empire.
Sombra's magic is slowly consuming all of Equestria, and the ponies need the help of the most unwilling human to survive. It is for his own sake as well.
Dark Souls crossover. A young stallion's journey to rescue a friend from a decaying asylum leads to an adventure through the ancient, ruined kingdom of Equestria.
Hybridization of MLP+Inception. Shortly after Twilight finishes a spell that allows her to enter the subconscious through dreams, the Mane Six must perform an inception on Spike when his mind becomes threatened by a split personality. Featured on EQD
Apple Bloom and Rumble are bored out of their minds. All they have is each other for one week. On the second day, they decide to go and explore a cave in the mountains near Ponyville.