Fluttershy is no longer herself and needs convincing from her friends to return to normal. However, the more they try, the more distant she becomes, and Twilight worries that they may lose their friend forever.
A changeling suffers from an embarrassing affliction that causes him to shape shift whenever he has the hiccups. Dealing with it is half the problem, when Chrysalis also sends him on an infiltration mission as well.
When she was in middle school, Sunset Shimmer suffered from what is called 'Middle-second syndrome'. Finding her past embarrassing, Sunset will try everything to start her high school journey quietly after moving out from her city.
Turns out Rainbow Dash and Rarity are a married couple, and have been since before Twilight moved to Ponyville. Twilight never knew this. Hilarity ensues, as well as a few feels.
Going on an inter-dimensional date with her marefri—sorry, girlfriend—was not supposed to lead to the existential crisis of a lifetime, but there was Rarity anyway.
Anon describes a board game from home, and Twilight arranges a game night to recreate it. This proves to be a greater threat to their friendship than anything they have faced.
The day Twilight earns her cutie mark, something unexpected happens that no pony saw coming. Twilight undergoes a transformation due to an absurd amount of magic and literally becomes the spirit of magic.
Princess Skystar wants to join her cousin Silverstream at the School of Friendship after feeling like her mother doesn’t spend enough time with her. Unfortunately, Queen Novo still has some negative feelings towards Twilight that she has to sort out…
The variable nature of autumn makes it impossible for a dignified mare like Rarity to properly dress for the weather. Clearly the thing to do is altering the schedule through breaking into Rainbow's office. Isn't that right, Twilight?