The Princesses find an alien creature barely clinging to life at the scene of a terrifying crash. Can the Combined Power of the Elements of Harmony save it, or more importantly, should they save it? Will the arrival of this strange creature tear Equestria apart?

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https://tvtropes.org/pmwiki/pmwiki.php/FanFic/Article2

In the many years after the Conversion Bureaus' shutdown, Twilight Sparkle is tasked by the Princesses with finding the last living human on Earth, Isaac Hamilton, and learning the story of his past. What she hears is a tale of loss, tragedy, joy, and the discovery of one's place in the world. But how much longer would that place last with what Twilight has to tell him?

Robert Parker is a 24 year old ex-web developer living in New York city. In the wake of the conversion movement, he has seemingly lost everything. Haunted by the same nightmare every night, he soon realizes that he must make a choice.

To those unfamiliar with the Conversion Bureau: it is a scenario created by an author named blaze in which Ponies either appear in the human world or have lived beside humans without incident for millennia. One day, in the face of all the damage humanity has done to its world, the ponies offer a solution: undergo conversion to become a pony and allow the world to be inundated with Equestria's influence: thus healing it and bring forth a golden age.

Many different authors have taken many different approaches to this idea, all of them are worth checking out.

http://www.ponychan.net/chan/fic/res/53616.html (The current thread)
http://www.equestriadaily.com/2011/04/conversion-bureau-compilation.html (The compilation post on EQDaily. *NOT UPDATED*)

Brought to you by Loyal2Luna, this new Downloadable Content for Mass Effect 2 brings the fight to Equestria.

Just about ready to embark on their mission to stop the Collectors from further abducting human colonies, Commander Shepard and the crew of the Normandy SR-2 are given a new priority, when the Illusive Man tasks them with investigating the mysterious disappearance of a Cerberus science team.

Soon, what begins as a simple search-and-rescue unveils a mystery millions of years in the making, and the Commander finds himself thrust into a situation he couldn't possibly have prepared himself for.

Join the Hero of the Citadel as he uncovers the secrets, combats the demons, and ultimately decides the fate of the impossible world known as "Equestria."