Disaster strikes when a highly contagious disease threatens to drive all the ponies of Ponyville insane. When this sickness is so hazardous that even Princess Celestia can do nothing to help, Ponyville is sealed in a barrier to stop the disease from spreading. On their own, how will the ponies cope with everypony on the verge of insanity? Will they ever find a cure?

“The sidewalks are empty,/The bars and cafes too./The streetlights only changing,/'Cause they ain't got nothing better to do.” -Benjamin Gibbard, ‘Life In Quarantine’

Sequel: “Life In Quarantine 2: Friends”

With the lockdown in place, the girls of Canterlot High are trying to their best to keep themselves busy and stay sane as they stay in quarantine. Thankfully, they each have their cell phones.

UPDATE 7/29/2020: Reformatted, edited, and reposted after taken down due to issues.

Stuck at college with only a housemate and a dog for company, Sunset Shimmer vlogs to cope with the COVID-19 lockdown. Let’s see if it catches on.

Teen because I'm not entirely sure where this is going to go. This will be somewhat audience driven, in that other characters and vlogs may be added if there's an interest.

My Little Pony and its characters are owned by Hasbro and its affiliates. I have no clue who owns the memes so... I guess they're the property of whoever made them? I don't know. I ain't a lawyer.

Humans.

Truth or myth? Ancient lost civilization or just an old pony's tale?

No pony has ever seen one, and most haven't even heard of them. But Lyra knows that these wonderful creatures are more than just old legends, and she's going to find out... and possibly drive her roommate insane in the process.