There=place
Their=shows possession
They're=they are
Lay=an action done to something else "He layed down the remote"
Lie=an action done to oneself "He lied on the bed"
Your=shows possession
You're=you are
To=position "He went to the fridge"
Too=occasionally replaces 'also', and used in saying stuff like 'too much' or 'too many'
Two=twice as many as one, but half as many as four