An accident with the Mirror Portal ends up with Twilight stuck as a small pony in the Equestra Girls' world. Her friends can't get over how cute she is.
A year has passed since Twilight was forced to leave a dying Spike to an elder dragon, without being granted the privilege of knowing his fate. Worried on how she'll cope after the utter silence, she fears what might be waiting for her one year later
In the near future mankind was driven into a biochemical war against an unidentifiable contagion created by an asteroid that struck the planet. Without no cure or any form of escape, mankind buried themselves and awaited their extinction.