Not hearing anything in space is not an excuse to never scream at all. Especially when you want to become famous, rich, part of high society and possibly find love along the way doing it.
Fluttershy is a long way from home; will she survive the harsh and crazy universe while exploring its many wonders? She loves everything after all, now she has to prove that she does and it may just keep her alive.
Kazooie has returned as a princess once more. Is that actually a good thing when she's trying to take over Equestria? With the help of her friends and assuming she can actually focus on her goal, she just might actually suceed.
Screwball and Kazooie travel the video game realms. Screwball learns to be a cartoon character. Chaos breaks loose, then gets bored and joins them. Derpy doesn't have a clue what could go wrong or how she got involved.