So, it appears the rumors are true...DJ Pon-3 and even Rarity have been bitten by bat-ponies...vampire ones! Vampire bat ponies are now common in Equestria, but who would have thought that two heroes would have been affected by them?!
Set after "We Regret to Inform You" :D Pinkie Pie becomes a mother of six children, not including Pound and Pumpkin Pie-'cake'. Pinkie and Cheese then marry and have kids. The Twins now have to deal with sextuplet additions, making a huge family! :)
Future universe. "Sister" Princesses Sunset Shimmer and Twilight Sparkle mourned the loss of Equestria's favorite Princesses - The royal natural-born alicorn sisters Celestia and Luna. In an attempt to win them back, they resurrect them - as fillies.