Long story short, humanity thought it was a good idea to kill itself not with pollution or nukes, but with bio-weapons. I was the lucky one as I was somehow resistant to the changes everyone went through and only benefited from them. She wasn't sadly
Spike, banished from Ponyville for a crime he didn't commit, he is'd discover by someone he didn't expected, and sent to somewhere were the beginning of his new adventure and life starts
Goku inadvertently lands on a new world on his way to planet Namek. Now, with his ship in disarray, Goku new adventures on the planet called Equis is about to begin. Where he sure he meet new friends as well as enemies.