Venom, Ultimate Nemesis to Spider-Man, the Lethal Protector, one of the many great anti-heroes, are doing their job as usual. Getting stuck in Equestria, however, definitely was not what they expected.
Twilight teleports herself ten years into the future without realizing her spell was a one-way trip. Now stuck in a world that hasn't seen her in a whole decade, she's forced to see how her friends' lives have fallen apart. DECADE LONG HAITUS OVER!
Humanity's space exploration ultimately took the form of billions of identical probes, capable of building anything (including astronauts themselves) upon arrival at their destinations. One lands in Equestria. Things go downhill from there.