Twilight has gotten sick, over the past few weeks, Spike has not left her side. He has done everything Twilight has asked him to do. But when Twilight asks him to leave, Spike soon has to face a truth he had never wanted to think about. But miracles have been known to happen, even if they do come with dire consequences.

This story is a sequel to Friendship isn't all you will need in life

After the events of 'Friendship isn't all you will need in life' Fluttershy and Discord are now a couple. Spike now has far better chances to get with his crush, thanks to that.

Set back at the start of "Keep calm and flutter on" Fluttershy decides to befriend Discord, after they get used to each other, everything seems fine. Until they find out about something Celestia found. Will the actions between Fluttershy and Discord strengthen their relationship as, "friends"? Or will Fluttershy's friends do the opposite?