Ever since she first became a princess, Twilight faced hardships. Her only solstice is in the company of a being she met in another plain of reality. Then one day Equestria is greeted by aliens that believe Twilight to be their god.
"With the vast, endless ocean of the Warp and the infinite web of the Multiverse a definitive factor; all possibilities are possible, all realities are real." - (I do crossovers a lot)