What Pokemon would they be? What would their life be like? Would they have a trainer?

(It doesn't have to make "sense", anymore than Fluttershy has to qualify as a pegasus. I myself have a random idea of Twilight Sparkle as a Buneary, which is pretty darn random.)

6969910 I can see Shining and Cadance being Gallade and Gardevoir

6969919
Hmm... possible. Gallade seems like a bit of an offensive build though - can it be respecced as a stone wall?

(Yes, I know I said it didn't have to makes sense.)

6969910
I would see Fluttershy as either a Chansey, or a Togekiss. For Rarity, she would be a Sylveon or Gerdevoir. For Spike, either a Charmander, Dratini, Gible, Axew , or Goomy. As for the rest, I'm not sure.

6969943
Could definitely see Flutters like that. Rarity too, maybe. And most of those work for Spike - I've thought of pairing a Gible version with the Buneary Twilight from above.

6969910
Rainbow Dash is definitely a Staraptor, and I can personally see Twilight as a Duosion or a Reuniclus.

6971208
Hmm... plausible, even if I find that second line a bit creepy.

6971212
Oh shoot, how did I not notice how that would sound?!

Maybe Espeon would be a better choice for Twilight.

6971217
No, not your phrasing - I meant the Solosis line. And it might - I do like Buneary, but it can't really learn active Psychic moves. Ah well, SciTwi manged most of her life without...

6971225
Yeah, for some reason, my mind blanked when trying to think of Psychic-type Pokémon that Twilight could be, and all I could think of were the Abra line and the Solosis line. Oof.

6971231
Well, I don't think it's an odder take than mine - you went for the amazing power, I went for the cute and anti-social. But Espeon may well be the best fit, being a friendship evolution.