131) "Pants!, I choose you!"
~Pokemon

132) "I wanna be, the very best, like no pants ever was. To catch them is my real test, to train them is my cause. I will travel across the land, searching far and wide. These pants to understand, the power that's insiiiiide!"
~Pokemon intro.

133 - "Need some pants here!"
(Sniper, TF2, Help Quote)

134 - "One time I tried to hold in a fart at school and when it came out it ripped my pants off."
(Owen, Total Drama World Tour "Sweeden Sour")

135 - "Pants! Pants on my face! Help!"
(Pinkie Pie, MLP FiM "Ticket Master")

136 - "Come Bakura. Let us atain his leather pants."
(Marik Ishtar, Yu-Gi-Oh! Abridged Leather Pants)

137 - "Quick don't think about pants!"
(Random Guy, ASDF Movie 6)

138 - "I like pants."
(I like trains kid, ASDF Movie 2)

139 - "When I get ahold of you I'm gonna pull out your eye balls and shove em down your pants! So you can watch me kick the crap out of you, o.k.?!"
(Moe, The Simpsons)

140 - "Pants and I are coming for you."
(Heavy, TF2, Sandvich Quote)

141 - "According to this *Shows chart* your track rates for selling pants is pathetic!"
(Uka Uka, Crash Bandicoot The Wrath of Cortex!)

142 - "We'll leave skid marks! Not the kind in your pants."
(Crunch Bandicoot, Crash Tag Team Racing)

143) "A lie gets halfway around the world before truth gets its pants on." (Winston Churchill)(No words changed)

144) "If you could kick the person in the pants most responsible for your troubles, you wouldn't be able to sit for a month." (Theodore Roosevelt)(no words changed)

145)
Equestria Girls are pony-fabulous.

Boots on hooves, pants on top.

BONUS POINTS!

(By the way, my family is laughing at pants- especially because we saw a guy walking down the street carrying his pants over his shoulder! )

146) May the pants be with you.

(Star Wars)

904183 Someone already posted that.

147 - "Grabbin pants."
(Louis, Left 4 Dead)

148 - "You know what I don't hate, I don't hate pants."
(Francis, Left 4 Dead)

149 - "I am going to strangle you with your own filfthy training pants!"
(Solider, TF2, Domination Quote)

150 - "No one wears pants like Geston."
(Geston, Disney's Beauty and The Beast)

151 - "The Great and Powerful Trixie doesn't trust panties."
(Trixie, MLP FiM "Magic Duel", Possible Equestria Girls quote)

152 - "I really do like the pants."
(Bakura, Yu-Gi-Oh! Abridged Leather Pants)

153 - "Pants. More then meets the eye."
(Transformers Slogan)

154 - "I'll get you Captain Underpants!"
(Professor PoopyPants, Hooray for Captain Underpants)

155 - "You dare bring pants to my liar?! YOU MUST DIE!"
(Ganon, Legend of Zelda Philips CDI)

156 - "If you have any pants fling em now."
(Mason, Madagascar)

157 - "That's ridicolicolicolius! I mean who wears pants anyway?"
(Ebenezar Von Clutch, Crash Tag Team Racing)

158 - "Wave goodbye to your secret pants dumbass!"
(Scout, TF2 Intel Securing Quote)

904324

Which one?

905249 May the pants be with you.

Since noone else seems to be posting any pants lines

159 - "Dah! Underpants!'
(Melvin, Madagascar)

160 - "Son I'm gonna blow that dumb look right off your stupid pants."
(Engineer, TF2, Domination Quote)

161 - "Alert. The enemy has taken our pants."
(Anouncer, TF2, Inteal Stolen Quote)

162 - "Pants here."
(Louis, Left 4 Dead)

163 - "We hold these truths to be self evident. That all pants are created equal."
(The preamble of the Decleration of Independence)

164 - "Kiss my pants bitch I'm immortal!"
(Krillin, Team Four Star Dragon Ball Z Abridged Episode 25)

165 - "O.k. Marik. Though I have to say I had no idea you were this keen to get into the Pharoh's pants."
(Yami Bakura, Yu-Gi-Oh! Abridged Leather Pants)

166 - "Attention duelists! My pants have an announcement to make!"
(The Hair Guy, Yu-Gi-Oh! Abridged)

167 - "Silly pants."
(Scootaloo, MLP FiM "Sleepless in Ponyville)

168 - "Well I was hungry and well you know when you crave pants."
(Carl, Llamas with Hats)

169 - "Quick shoot me in the pants!"
(Random Guy, ASDF Movie)

170 - "With the power of these pants I will be stronger then him!"
(Shadow, Shadow The Hedgehog)

171 - "No pair of pants in the universe is going to stop me!"
(Sonic, Sonic Colors)

172 - "Gaint pants activate."
(Rarity, FiW "Dragone Baby Gone")

CLASSIC MOVIE EDITION!

173. "Pants..."
-Charles Foster Kane, Citizen Kane.

174. "Fasten your pants, it's gonna be a bumpy night."
-Margo Channing, All About Eve

175. "Here's looking at you, pants."
-Rick, Casablanca

176. "I'm gonna give'em a pants he can't refuse."
-Don Corleone, The Godfather I

177. "I'm king of the pants!"
-Jack, Titanic

178. "I'm still big, it's the pants that got small."
-Norma Desman, Sunset Blvd.

179. "Alright, Mr. DeMille, I'm ready for my pants."
-Ibid.

180. "Lousy kids, you give your pants out for them!"
-Juror#3 (acted by the great Lee J. Cobb), 12 Angry Men

905258

How about may the force be with pants?

907363 O.k. That counts as 181

182 - "There are squirrels in my pants!"
(Candence, Phenias and Ferb)

183 - "Always two there are. No more no less. A wearer and a pair of pants."
(Yoda, Star Wars Episode I The Phantom Meance)

184 - "I promise you pants without end."
(Heavy, TF2, Domination Quote)

185 - "Ho, pants, huh."
(Medic, TF2 Meet The Medic)

186 - "Don't be difficult fluffy only one of us can wear the pants."
(Marik, Yu-Gi-Oh! Abridged Leather Pants)

187 - "I'm going to punch your pants. In the pants."
(Random guy, ASDF Movie 6)

188 - "O.k. who has the pants?!"
(Freiza, Team Four Star Dragon Ball Z Abridged Episode 25)

189 - "I'd like to be a pair of pants."
(Fluttershy, MLP FiM "Over A Barrel")

190 - "This isn't about you this is about me and my gaint pants."
(Rarity, FiW "The Perfect Swarm")

191 - "Isn't it fancy pants?"
(Pinkie Pie, MLP FiM "Sweet and Elite")

192 - "If the pants fit!"
(Woody, Toy Story 2)

193 - "No my space pants!"
(Raditz, Team Four Star Dragon Ball Z Abridged Episode 2)

194 - "Nopony at the school takes pants seriously."
(Diamond Tiara, MLP FiM "Ponyville Confidential)

195 - "With malice toward none. With pants toward all."
(Abraham Lincoln's Second Innagural Address)

196 - "Gentlemen behold! Pants!"
(Dr. Weird, Aqua Teen Hunger Force)

197 - "And that's the art of the pants."
(Rarity, "Art of The Dress")

198 - "Now the day's been saved and peace has been restored. And Captain Underpants isn't needed anymore."
(Hooray for Captain Underpants)

199 - "Sugar. Spice. And everything nice. These were the ingredients choosen to create the perfect pants."
(Powerpuff Girls Opening)

200 - "I will not tolerate pants on my team."
(Solider, TF2 Round Start Quote)

908129

I can change my other one to that.

908358 Probably shouldn't since I already posted it.

201 - "This American boot just kicked your pants back to Russia."
(Solider, TF2 Heavy Domination Quote)

202 - "Long live the pants."
(Scar, Disney's The Lion King)

203 - "The only thing we have to fear is pants themselves."
(Franklin D. Roosevelt's First Innagural Address)

204 - "Then he used his fight money to buy two of every pair of pants on Earth."
(Solider, TF2 Meet The Solider)

205 - "Soundwave superior, pants inferior."
(Soundwave, The Transformers The Movie)

206 - "And I stabbed him 37 times in the pants."
(Carl, Llamas with Hats)

207 - "Why throw away your pants so wrecklessly?"
(Megatron, The Transformers The Movie)

208 - "Oh they'll have to sew your pants back together in hell!"
(Demoman, TF2 Meet The Demoman)

209 - "Ich ben I'n just kicked your pants!"
(Solider, TF2 Medic Domination Quote)

210 - "Hey lard fat those pants don't stop bullets do they?!"
(Scout, TF2 Heavy Domination Quote)

211 - "Don't run. It's just pants."
(Heavy, TF2 Sandvich Quote)

212 - "Applejack's trying to make pants."
(Twilight Sparkle, MLP FiM "A True, True Friend")

213 - "Yes but my pants give me the power to defy gravity."
(The Hair Guy, Yu-Gi-Oh! Abridged Episode 6)

214 - "Your mother wears pants in hell!"
(Teddy, Yu-Gi-Oh! Abridged Episode 20)

215 - "Who keeps throwing these random pants at me? It's not funny you know. Stop it!"
(Yami, Yu-Gi-Oh! Abridged Episode 10)

908688

"Applejack's trying to make pants."

Why does this sound like it fits in the cutie mark swap all too well?

909981 Because it does.

218 - "What was that pants? Kill them all? Good idea. Ahahaha."
(Heavy, TF2 Sandvich Quote)

219 - "Oh no my friends don't like my pants and they don't wanna be my friends anymore."
(Pinkie Pie, MLP FiM "Party of One")

220 - "Pants Q?"
(James Bond, Moonraker)

221 - "But one day an autobot shall rise from our ranks. And use the power of the pants to light. Our darkest hour."
(Optimus Prime, The Transformers The Movie)

222 - "It's a bird, it's a plane, it's a egg salad sandwitch. No way! He's Captain Underpants."
(The amazing Captain Underpants)

223 - "It is time to make da pants."
(Photo Finish, MLP FiM "Green Isn't Your Color)

224 - "Trust your pants."
(Qui-gon-jin, Star Wars Episode I The Phantom Meance)

225 - "Stick with me and you'll never wear pants again!"
(Scar, Be Prepared)

226 - "Finally I get to wrap my fingers around your puny orange pants."
(Crunch Bandicoot, Crash Bandicoot The Wrath of Cortex)

910375

"Oh no my friends don't like my pants and they don't wanna be my friends anymore."

227. "Dressed? We don't normally wear pants." (Applejack, My Little Pony: Friendship is Magic "The Best Night Ever")

228. "I'll catch you yet my pretties. Oh yes, as soon as one of you little birds or monkeys or bears touches these pants you'll be mine! MINE!" (Fluttershy, My Little Pony: Friendship is Magic "The Best Night Ever")

229. "My letter to Princess Celestia is almost due and I haven't learned anything about pants!" (Twilight Sparkle, My Little Pony: Friendship is Magic "Lesson Zero")

230. "Enough chit-chat! Time is pants!" (Pinkie Pie, My Little Pony: Friendship is Magic "Luna Eclipsed")

231. "Too old for free pants? Never." (Pinkie Pie, My Little Pony: Friendship is Magic "Luna Eclipsed")

232. "And I was like pants are you crazy?" (Pinkie Pie, My Little Pony: Friendship is Magic "The Ticket Master")

233. "You're more than friends. You're my pants." (Spike, My Little Pony: Friendship is Magic "Dragon Quest")

234. "Fine I'm guilty! I wear false eyelashes. Oh, and I took a bite of the pants." (Rarity, My Little Pony: Friendship is Magic "MMMMystery on the Friendship Express")

235. "I'm just glad I haven't been replaced by a bucket of pants." (Rainbow Dash, My Little Pony: Friendship is Magic "Party of One")

236. "My pants!" (Soarin, My Little Pony: Friendship is Magic "The Best Night Ever")

237. "Remember this shirt little ponies, for it was your last. From this moment forth, the pants will last FOREVER!" (Nightmare Moon, My Little Pony: Friendship is Magic "Friendship is Magic Part 1") [I wish that was the case sometimes ]

238. "Afraid to get PANTS?" (Rarity, My Little Pony: Friendship is Magic "The Best Night Ever")

239. "A rock? That's my destiny? What is your problem pants? I followed you all the way out here for a rock?!" (Rarity, My Little Pony: Friendship is Magic "The Cutie Mark Chronicles")

240. "Dumb pants!" (Rarity, My Little Pony: Friendship is Magic "The Cutie Mark Chronicles")

241. "These namby pambly stories aren't getting us anywhere closer to our pants!" (Scootaloo, My Little Pony: Friendship is Magic "The Cutie Mark Chronicles")

242. "Pants? Come with me and I'll tell you how I got mine!" (Pinkie Pie, My Little Pony: Friendship is Magic "The Cutie Mark Chronicles")

I think that's enough from me for today...

243 - "What pants?"
(Rarity, MLP FiM "Sweet and Elite")

244 - "Underpants is faster than, a speeding waistband."
(The Amazing Captain Underpants)

245 - "Underpants, underpants, I like Captain Underpants."
(Hooray for Captain Underpants)

246 - "You underestimate my pants Galvatron."
(Unicron, The Transformers The Movie)

247 - "Any pants you can wear I can wear better."
(Trixie, MLP FiM "Boast Busters")

248 - "You're going to LOVE PANTS!"
(Fluttershy, MLP FiM "Best Night Ever")

249 - "Where's your precious pants now?"
(Scout, TF2 Medic Domination Quote)

250 - "I love pants."
(Rainbow Dash, MLP FiM "Suited For Sucess")

251 - "Meanine pants! Take this!"
(Pinkie Pie, MLP FiM Promo)

252 - "Did someone say pants?"
(Peter Griffin, Family Guy)

253 - "He's got pants now?"
(Willis, Digimon The Movie)

254 - "I hate pants!"
(Spy, TF2)

255 - "Beg pardon Rarity but uh we don't normally wear panties."
(Applejack, MLP FiM "Best Night Ever") (Possible Equestria Girls quote)

256 - "YOU ARE A PAIR, OF PANTS!"
(Woody, Toy Story)

257 - "Holy pants on a pants sandwhich."
(Tristan, Yu-Gi-Oh! Abridged Episode 20)

258 - "How embarassing. Zey let a man of science escape with ze pants."
(Medic, TF2 Intel Securing Quote)

259 - "And from that day forward any time a bunch of pants are together in one place it's called a laundromat! Unless it's a tailor!"
(Solider, TF2 Meet The Solider)

260 - "Able to leap tall buildings without getting a wedgie. Trlalala he's Captain Underpants."
(The Amazing Captain Underpants)

261 - "PANTS! I will cut you, with a knife!"
(Chuggaconroy, The Runaway Guys Mario Party)

262 - "One shudders to imagine what inhuman thoughts lie behind those pants."
(Spy, TF2 Meet The Pyro)

263 - "Captain Underpants should fly by my school."
(Hooray for Captain Underpants)

264 - "Bite my glorious golden pants!"
(Bender, Futurama)

265 - "Pants 007."
(Q, Moonraker)

266 - "They flew pants of many hues."
(Rarity, Legend of The Crystal Empire)

267 - "Bite my shiny metal pants!"
(Bender, Futurama)

268 - "You're going to knock everypony's pants off at the Equestria rodeo."
(Apple Bloom, MLP FiM "The Last Roundup")

269 - "She should've just peed in her pants like Cody."
(Heather, Total Drama Island "The Sucky Outdoors")

270 - "Gentlemen! I bring you, more pants!"
(Dr. Weird, Aqua Teen Hunger Force)

271 - "Captain Underpants, Captain Underpants. Greatest hero, greatest hero."
(The Amazing Captain Underpants)

272 - "Cute and comfy pants. Cute and comfy!"
(Skipper, Madagascar)

273 - "We've got to have PANTS."
(Dr. Lickboot, Tom and Jerry Movie)

274 - "But if I win I'll turn your entire globe into a pair of pants!"
(Nitrious Oxide, Crash Team Racing)

275 - "Pants Starscream? This is bad comedy."
(Galvatron, The Transformers The Movie)

276 - "It's not about winning. It's about pants."
(Spongebob, Spongebob Squarepants)

277 - "Screw the rules I have green pants."
(Kaiba, Yu-Gi-Oh! Abridged Episode 11)

278 - "Underpants, underpants. Hooray for Captain Underpants."
(Hooray for Captain Underpants)

279 - "What are these pants thou speakest of?"
(Princess Luna, MLP FiM "Luna Eclipsed")

280 - "I'm the pants critic. I wear it so that you don't have to."
(Nostalgia Critic)

281 - "I'll get you next time pants. Next time."
(Dr. Claw, Inspector Gadget Credits Squence)

282 - "We do not talk about pants in this house young lady!"
(Nostalgia Critic, Twister)

283 - "I'll get you my pretty and your little pants too."
(The Wicked Witch of The West, The Wizard of Oz)

284 - "But it's got to be my destiny, cause it's what my pants are telling me."
(Pinkie Pie, MLP FiM "What My Cutie Mark is Telling Me")

285 - "Yes Terry! Mine for pants!"
(Dr. Weird, Aqua Teen Hunger Force)

286 - "Is it safe to be wearing those pants? THEY LOOK FLAMABLE!"
(Pyro, Crash Bandicoot The Wrath of Cortex)

287 - "Er I'm okay. The pants broke my fall."
(Cortex, Crash Twinsanity)

288 - "I wear pants!"
(Rarity, MLP FiM "MMMystery on The Friendship Express)

289 - "At last the source of the Pharoh's power. His leather pants. They belong to me."
(Marik Ishtar, Yu-Gi-Oh! Abridged Leather Pants)

290 - "Do ponies wallow in pants?"
(Rarity, MLP FiM "Suited For Sucess")

291 - "This is Smarty Pants."
(Twilight, MLP FiM "Lesson Zero")

292 - "Ma boy. These pants are what all true warriors strive for."
(The King, Legend of Zelda Philips CDI)

293 - "Hey let's throw pants at him and see how he likes it!"
(Random Bikini Bottom Citizen, Spongebob Squarepants "The Smoking Peanut")

294 - "Captain Underpants I can get your autograph?"
(Fan girl, Hooray for Captain Underpants)

295 - "Don't touch those! Those are my pants."
(Q, Goldeneye)

296 - "If I can't find a pants problem, I'll make a pants problem."
(Twilight, MLP FiM "Lesson Zero")

297 - "Is it a crime to change one's pants every now and then?!"
(Rarity, MLP FiM "MMMystery on The Friendship Express)

298 - "Am I the only one who thought of Frieza with pants?"
(Krillin, Team Four Star Dragon Ball Z Abridged Episode 32)

299 - "Ask not what pants can do for you. Ask what you can do for pants."
(John F. Kennedy's Innagural Address)

300 - "Those pants need to be condemed."
(Spike, MLP FiM "Winter Wrap Up")

301 - "Hey, hey, hey. What'd I tell yal about comin into my pants?"
(Fluttershy, Shed. MOV)

302 - "My name is Professor Pippy P. Poopy Pants."
(Professor Poopy Pants, Go Poopy Pants)

303 - "Leave my pants alone!"
(Wa Wa, Crash Bandicoot The Wrath of Cortex)

304 - "There is no pants issue here."
(Lyndon Johnson's address on the 1964 Civil Rights Bill)

305 - "My thanks to all pants."
(Robert "Bobby" F. Kennedy's last public words, his speech celebrating his victory in the 1968 California Democratic primary)

306 - "You're a-a pair of pants!"
(Gilda, MLP FiM "Griffon The Brush Off")

307 - "So. I see you recieved the free pants I sent you."
(The Joker, Batman The Killing Joke)

308 - "Without Captain Underpants. We haven't got a chance."
(Go Poopy Pants)

309 - "Dance. Dance. Captain Underpants pizza party."
(Captain Underpants Pizza Party)

310 - "You know who's got a lot of pants, guys who bludegon their wifes to death with a golf trophy."
(Sniper, TF2 Meet The Sniper)

311 - "I don't care about ponies pants!"
(Diamond Tiara, MLP FiM "Ponyville Confidential)

312 - "Go to hell and take your cheap pants with you."
(Spy, TF2 Spy Dominating Quote)

313 - "If wearing pants is sure to result in victory then you must wear pants."
(Soldier, TF2 Meet The Soldier)

314 - "My foot will transform into a foot with your pants wrapped around it."
(Soldier, TF2 Robot Costume Quote)

315 - "Were you snooping through my pants?!"
(Sweetie Belle, MLP FiM "Ponyville Confidential")

316 - "I will mail my boot to the Kaiser with your pants wrapped around it.
(Soldier, TF2 Medic Domination Quote)

317 - "Not one of your pants is gonna survive this!"
(Demoman, TF2 Meet The Demoman)

318 - "I'll make you a pair of pants as well."
(Rarity, MLP FiM "Suited For Sucess")

319 - "Captain Underpants Pizza Party at my school."
(Captain Underpants Pizza Party)

320 - "You gotta spend a lot of time fighting mean stuff. Like talking toilets and Professor Poopypants."
(Hooray for Captain Underpants)

321 - "I find your lack of pants disturbing."
(Darth Vadar, Star Wars Episode IV A New Hope)

322 - "Oh I'm gonna shake, rattle, and roll your bandicoot pants."
(Rocko, Crash Bandicoot The Wrath of Cortex)

323 - "Pants. Great pants have come."
(Aku Aku, Crash Bandicoot Warped)

324 - "So you pesky little earth slugs like to wear pants eh? Hehehehe."
(Nitrious Oxide, Crash Team Racing)

325 - "Those pants are a joke."
(Crunch Bandicoot, Crash Nitro Kart)

326) We dreamed of creating the world's strongest pants. We succeeded.
(Scientist. Pokémon the First Movie. one change)

327) Thank you for nothing, you useless pants.
(Hiccup. How to Train Your Dragon. one change)

328) In the dark of the pants evil will find her!
(Rasputin. Anastasia. one change)

329) You're playing with the big pants now.
(The Prince of Egypt. one change.)

330) So you think you have friends in high pants...
(The Prince of Egypt. One change)

331) Ah the new boy. The ears are too long, and I miss the pants, but not too shabby. Not too shaby at all. Wolf!
(The Joker. Batman Beyond Return of the Joker. one change)

332) Make a face. Drop your pants. Something.
(Batman. Batman Beyond Return of the Joker. no change)

919010 Those are 326-332

333 - "On the contrary Aku Aku. Spells disaster for you and those precious pants you care so much about."
(Pyro, Crash Bandicoot The Wrath of Cortex)

334 - "If you were hunting pants lad you found em."
(Demoman, TF2 Domination Quote)

335 - "We need to protect the pants."
(Soldier, TF2 Meet The Spy)

336 - "Enough! *Slap* I'm tired of your big bad pants act!"
(Davis/Daisuke, Digimon Adventure 02 episode 26)

337 - "Airbag's a little slow *airbag inflates* but that what these pants are for."
(The Grinch, Dr. Sesus' The Grinch 2000 Movie)

338 - "Really 007 just once I'd like to get a pair of pants back in one piece."
(Q, James Bond Nightfire)

339 - "He's always wanted his own pair of riding pants?"
(Pinkie Pie, MLP FiM "Just for Sidekicks")

340 - "They're going to have to hang your pants out to dry when I get through with you!"
(Wa Wa, Crash Bandicoot The Wrath of Cortex)

341 - "Crash! Coco! Stole the pretty pants!"
(Tiny Tiger, Crash Bandicoot Warped)

342 - "Only the Avatar master of all 4 pants could stop them."
(Katara, Avatar The Last Airbender Title Squence)

343 - "Those were no pants! That was a damned radar!"
(Vegeta, Dragon Ball Z Kai Uncut Edition)

344 - "Go pants. Lovely pants."
(John Lennon, The Beatles Yellow Submarine Movie)

345 - "This organization does not tolerate pants."
(Blofeld, You Only Live Twice)

346 - "All it takes is one bad day to reduce the sanest pants alive to lunacy."
(The Joker, Batman The Killing Joke)

347 - "Huzzah! How many pants do I recieve?"
(Princess Luna, MLP FiM "Luna Eclipsed")

348 - "Release me fast or you will have to answer for these haneous pants."
(Santa Clause, "The Oogie Boogie Song")

349 - "Oh I get it. Pants. Fight. Fun."
(Twilight, MLP FiM "Look Before You Sleep")

350 - "Are you saying my mouth is makin promises my pants can't keep?!"
(Applejack, MLP FiM "Applebuck Season")

351: "Our village has been pantsed by a Pants that pants pants." (Smurfs episode)

919472 Are you even paying attention to the numbers? That should be 351. Not trying to sound mean.

352 - "Me and Bakura we will have our revenge. Him and me will take your leather pants."
(Marik Ishtar, Yu-Gi-Oh! Abridged Leather Pants)

353 - "There was a pair of crystal pants. That everypony liked to wear."
(Pinkie Pie, MLP FiM "Legend of The Crystal Empire)

354 - "Pants of The Beast King!"
(Leomon, Digimon Tamers)

355 - "Behold pants. I shall now defeat you with my superior mind prowers."
(Melvin, Yu-Gi-Oh! Abridged Episode 53)

356 - "Pants? Shoot I was just gonna wear my old work duds."
(Applejack, MLP FiM "Suited For Sucess")

357 - "Don't be absurd. My leather pants are not the source of my power."
(Yami, Yu-Gi-Oh! Abridged Leather Pants)

358 - "You're all mine pants!'
(Starscream, Transformers Armada "Cramp")

359 - "Do you like my new pants? They are size XXX Large."
(King Hippo, Mike Tyson's Punch Out/Punch Out feautring Mr. Dream)

360 - "If I can help others my pants are unimportant!"
(Angemon, Digimon Adventure Episode 13)

361 - "This is the boss and I'm sick of waiting. I want pants! And this time don't screw it up!"
(Giovani, Team Rocket Double Trouble)

362 - "My pants are greasy sweet."
(Dimitri, Sly 2 Band of Thieves)

363 - "Not use to the pants up here are ya wuss?"
(Lu Lu, Crash Bandicoot The Wrath Of Cortex)

364 - "For your pants only. Only for you."
(For Your Eyes Only, Shirely Easton)

365 - "Hope you brought your sunscreen because your pants are gonna burn!"
(Pyro, Crash Bandicoot The Wrath Of Cortex)

366 - "Scientists from the future have studied your pants for centuries. And have sent me back in time to kick them."
(Soldier, TF2 Robot Costume Quote)

367 - "The house rocked. Broken glass tinkled. Pants were everywhere."
(Thomas The Tank Engine and Friends, Thomas Comes To Breakfast)

368 - "Right. Now you've gone and done it. Them pants are mine."
(Dingodile, Crash Bandicoot Warped)

369 - "But Dr. Cortex. In order to reach full power we need not only your master pants. But also the remaining twenty five "slave" pants from the surface."
(N. Gin, Crash Bandicoot 2 Cortex Strikes Back)

370 - "Let's play pants games."
(Vector, Crash Twinsanity)

371 - "Check the pants."
(Johnny Bravo Title Squence)

372 - "I'm in pants heaven!"
(Sweetie Belle, MLP FiM "Just For Sidekicks")

373 - "I didn't know you could burn pants."
(Rarity, MLP FiM "Sisterhooves Social")

374 - "These pants in my sack, proves Von Clutch is a hack!"
(Willy Wumpa Cheeks, Crash Tag Team Racing)

375 - "Whoever stole the power pants has some connection to Wumpa Whip!"
(Coco Bandicoot, Crash Tag Team Racing)

376:

[Fluttershy]
Now, Rainbow, my dear, I cannot express my delight
It's abundantly clear
That somewhere out here
Are the pants that will suit you just right

[Rainbow Dash]
I can't wait to get started, but first let me set a few rules
It's of utmost importance
The pants that I get
Are something that's awesome and cool

Fluttershy: Awesome and cool, got it!
I have so many wonderful choices, just wait, you will see

[Rainbow Dash]
I need something real sleek and athletic to keep up with me

[Fluttershy]
Sure! How 'bout these boyshorts?
They're cutesy and wootsie and sleek as can be

[Rainbow Dash]
Cutesy, wootsie? Have you even met me?

Okay, I'm done. I can't do it any more, guys.

377 - "Sandvich and me going to beat your pants."
(Heavy, TF2 Sandvich Quote)

378 - "I appear to have burst in pants."
(Spy, TF2 On Fire Quote)

379 - "My pants! They burn!"
(Heavy, TF2 On Fire Quote)

380 - "Now most pants couldn't withstand this voltage. But I'm fairly certain your pants will *pants explode*"
(Medic, TF2 Meet The Medic)

381 - "I think it's time for Mr. Salty Pants to crack a smile."
(Murray, Sly 3 Honor Among Thieves)

382 - "His true power comes from, his leather pants."
(Marik Ishtar, Yu-Gi-Oh! Abridged Leather Pants)

383 - "I'm gonna beat you like a pair of pants boy!"
(Engineer, TF2 Domination Quote)

384 - "You know for pants."
(Nostaliga Critic, The Grinch 2000 Movie)

385 - "PANTS!"
(Nostaliga Critic, Twister)

386 - "Dingodile! Throw the pants!"
(N. Gin, Crash Nitro Kart)

387 - "Pants! *Slams checkerboard* I can squash pants!"
(Tiny Tiger, Crash Nitro Kart)

388 - "Protect the pants!"
(The announcer, TF2 Meet The Spy)

389 - "I see the pants are still safe."
(Spy, TF2 Meet The Spy)

390 - "It's over Anakin! I have the high pants!"
(Obi-Wan Kenobi, Star Wars Episode III Revenge Of The SIth)

391 - "Rarity loves pants!"
(Sweetie Belle, MLP FiM "Sleepless In Ponyville"

392 - "I think you dangerously underestimate my new pants!"
(Anakin Skywalker, Star Wars Episode III Revenge Of The Sith)

393 - "Best pants ever!"
(Rainbow Dash, MLP FiM "Sonic Rainboom")

394 - "Well I'm gonna do a pair of pants. *Presses* Oh."
(Random Guy, ASDF Movie 2)

395 - "Too much pants!"
(Timmy Turner, Fairly Odd Parents)

396 - "You who are without pants now plead for them? I thought you were made of sterner stuff."
(Optimus Prime, The Transformers The Movie)

397 - "Let the word go forth from this day and age. That the torch has been passed to a new generation of pants."
(John F. Kennedy's Innagural Address)

398 - "Careful 007! Those pants are very expensive!"
(Q, James Bond Nightfire)

399 - "But Dr. Cortex the pants are not ready. We have no idea what they could do. Hehehehehehe."
(Dr. Nitrious Brio, Crash Bandicoot)

400 - "Use the platform to deliver the pants to N. Gin!"
(Dr. Neo Cortex, Crash Bandicoot 2 Cortex Strikes Back)

401 - "What's the matter Ham?! Too much excitment for you?! Can't handle the big boy pants?!"
(SanJauro, TF2 2 Fort Interactive Adventure Do It Live)

402 - "And the Heavy just got stabbed in the pants!"
(SanJauro, TF2 2 Fort Interactive Adventure Do It Live)

403 - "Join me Link and I will make your pants the greatest in Corida. Or else you will die!"
(Ganon, Legend of Zelda Philips CDI)

404 - "Haha here's the problem too many pants."
(Mario, Hotel Mario)

405 - "Let's go practice pants."
(Medic, TF2 Meet The Medic)

406 - "My pants!"
(My Leg Guy, Spongebob Squarepants)

407 - "What is a man?! *Throws glass* A miserable little pile of pants!"
(Dracula, Castlevania Sympthy Of The Night)

408 - "Now I've got your pants."
(Megaman, Megaman Cartoon Episode 2)

409 - "Until that day. Til all pants are one."
(Optimus Prime, The Transformers The Movie)

410 - "I'll rip out your pants!"
(Megatron, The Transformers The Movie)

411 - "I use to be an adventure like you. But then I took an arrow to the pants."
(Castle Gaurd, Skyrim)

412 - "You'll be seeing your pants soon Star Fox."
(Wolf, Star Fox 64)

413 - "Congratulations Spike you're the new pants."
(Twilight, MLP FiM "The Return of Harmony Part 2")

414 - "No wait I'm allergic to pants."
(Random Guy, ASDF Movie 2)

415 - "King of the pants!"
(Garble, MLP FiM "Dragon Quest")

416 - "When I saw what a black awful pair of pants the world was I went crazy as a coot."
(The Joker, Batman The Killing Joke)

417 - "Be polite. Be efficent. Have a plan to kill every pair of pants you meet."
(Sniper, TF2 Meet The Sniper)

418 - "Indeed and now he's here to f*ck pants!"
(Spy, TF2 Meet The Spy)

419 - "Some people think they can outsmart me. Maybe *sniff* maybe. I've yet to meet one that can outsmart pants."
(Heavy, TF2 Meet The Heavy)

420 - "I solve pants problems."
(Engineer, TF2 Meet The Engineer)

421 - "I hurt pants!"
(Scout, TF2 Meet The Scout)

422 - "Don't forget the pants."
(Pinkie Pie, MLP FiM "Apple Family Reunion")

423 - "My 2 Fort has pants."
(Ham Samich, TF2 2 Fort Interactive Adventure Do It Live)

424 - "Read my lips no new pants!"
(George H.W. Bush, 1988 Campaign Pledge)

425 - "Now you're on your time you little skunk! GIVE ME THE PANTS!"
(Dr. Nefarious Trophy, Crash Bandicoot Warped)

426 - "My pants are on fire."
(Soldier, TF2 On Fire Quote)

427 - "Looks like we might be due for a big old storm of pants."
(Discord, MLP FiM "The Return of Harmony Part 1")

428 - "Anyone else starting to think these pants are a lost cause?"
(Applejack, MLP FiM "Crystal Empire Part 1")

429 - "I am. He who does not allow pants."'
(Great Sayiman, Dragon Ball Z Budokai 2 and 3)

430 - "Go Poopy Pants."
(Go Poopy Pants)

431 - "STOP RIGHT THERE CRIMINAL SCUM! Nobody breaks the pants on my watch!"
(Castle Guard, Elder Scrolls IV)

432 - "Pants must be destroyed!"
(Optimus Prime, Trasnformers Prime "One Shall Fall")

433 - "These pants aren't a toy Bumblebee!"
(Sari, Transformers Animated)

434 - "Gentlemen, fill me with pants because I'm dumb as hell!"
(Steve, Aqua Teen Hunger Force)

435 - "Hey, hey, hey, hey! Light the lamp not the pants! Light the lamp not the pants!"
(Rizo, Muppets Christmas Carol)

436 - "Enough excuses! You fine idiots need to come up with one good pair of pants! Or else!"
(Uka Uka, Crash Bandicoot The Wrath Of Cortex)

437 - "It is tradition to wear the royal pants!"
(Princess Luna, MLP FiM "Luna Eclipsed)

438 - "Be careful with those pants! Too late."
(Tobushcaius, Harry Potter and The Deathly Hallows Literal Trailer)

439 - "Ah! My pants!"
(Dr. Neo Cortex, Crash Tag Team Racing Car Damaged Quote)

440 - "I am NOT A PAIR OF PANTS!"
(Wheatley, Portal 2)

441 - "Pants are super easy to pack."
(Pinkie Pie, MLP FiM "Sweet and Elite")

442 - "Go and introduce a bat to his pants!"
(Luigi, Grand Theft Auto III)

443 - "Hell if you get a chance pop some of their pants too!"
(Tony, Grand Theft Auto III)

444 - "Shoot son you all as slow as pants."
(Enginner, TF2 Scout Domination Quote)

445 - "Wait why would Applejack steal some poor cat's pants? That's not very sporting of her."
(Pinkie Pie, MLP FiM "Fall Weather Pants")

446 - "Thank you Mario but our pants are in another castle."
(Toad, Super Mario Bros.)

447 - "Behold the ultimate pants!"
(Shadow, Shadow The Hedgehog Hero Meter Full Quote)

448 - "Oh for pants sake."
(Megatron, Transformers Animated)

449 - "Me Grimlock no like pants!"
(Grimlock, The Transformers The Movie)

450 - "Amazing. A pants trap that actually catches pants."
(Optimus Prime, The Transformers "Prime Target")

451 - "Noooooooooooooooo! It cannot be! What sort of pants were used to defeat I the great Uku-Uku?!"
(Uku-Uku, Crash Brash)

452 - "I wasn't prepared for pants."
(Twilight, MLP FiM "Failure Sucess Song", Possible Equestria Girls Quote)

453 - "No pants. No cheating."
(Aku-Aku, Crash Bash)

454 - "But you Vortex. You lost the gems. You lost the crystals. And I have lost my pants!"
(Uku-Uku, Crash Bandicoot Warped)

455 - "Poop pants. Go Poopy Pants. Go Poopy."
(Go Poopy Pants)

456 - "Go Poopy. Go Poopy Pants."
(Go Poopy Pants)

457 - "Go Poopy. Go Poopy Pants Go."
(Go Poopy Pants)

458 - "Captain Underpants likes wearing underwear."
(Hooray for Captain Underpants)

459 - "I think somepony's pants just got ripped."
(Babs Seed, MLP FiM "One Bad Apple")

460 - "I'm just glad none of them pants showed up."
("Rocky", MLP FiM "Party of One")

461 - "Fairy God Pants!"
(Mr. Denzil Crocker, Fairly Odd Parents)

462 - "Don't bring pants to a gun fight!"
(Scout, TF2 Engineer Domination Quote)

463 - "I mearly finished what your pants started."
(Spy, TF2 Demoman Domination Quote)

464 - "I will use your pants as toothpicks!"
(Jorgan, Fairly Odd Parents "Wish Fixers")

465 - "It wasn't all about money and who's got the latest pants."
(King Julian, "I Like To Move Move It Madagascar Remix")

466 - "I see London. I see France. I see X's underpants."
(Random Insult whenever someone's pants fall down, X is the name of the person)

467 - "The enemy has dropped our pants."
(The Anouncer, TF2 Intel Droping Quote)

468 - "Pants have been detected, and will be eliminated."
(The Anouncer, TF2 "Friendship" Quote from The Soldier v.s. Demoman War Event)

469 - "Vegeta what does the socuter say about his pants level?"
(Nappa, Dragon Ball Z Ocean Dub)

470 - "I am going to enjoy killing each and every one of you sorry sack of pants."
(Soldier, TF2 Domination Quote)

471 - "Pants never die."
(Tomorrow Never Dies, Sheryl Crow)

472 - "The pants are not enough."
(The World Is Not Enough, Garbage)

473 - "You've been pantsed baby!"
(Boingo, Hoodwinked)

474 - "Goldeneye I found his pants."
(Goldeneye, Tina Turner)

475 - "Pants are forever." (Bet we wish that was true)
(Diamonds Are Forever, Sheryl Basey)

927877

475 - "Pants are forever." (Bet we wish that was true)
(Diamonds Are Forever, Sheryl Basey)

I think I did that first copycat down here:

237. "Remember this shirt little ponies, for it was your last. From this moment forth, the pants will last FOREVER!" (Nightmare Moon, My Little Pony: Friendship is Magic "Friendship is Magic Part 1")

I kid, I kid

476. Oh he's a lumberjack and he's ok. He sleeps all night and wears pants all day!
Monty Python

477 - "Break out the needle. We're gonna make pants!"
(Dingodile, Crash Bandicoot Warped)

478 - "Well I've made a few "modifications" to my pants since our last encounter. So back off! Or be deleted!"
(N. Gin, Crash Bandicoot Warped)

479 - "Hey here's something you could invent next time, pants!"
(Scout, TF2 Engineer Domination Quote)

480 - "Johny. You forgot your pants."
(Johny's mom, Johny Bravo)

481 - "You either die a shirt. Or you live long enough to see yourself become the pants."
(Harvey Dent, The Dark Knight)

482 - "Goldpants."
(Goldfinger, Sheryl Basey)

483 - "Pants. James Pants."
(James Bond, Dr. No, Bond's First Line)

484 - "Do try to return these pants in useable condition, but I shan't hold my breath. Q out."
(Q, James Bond Nightfire)

485 - "Don't wonder why. My pants feel dead inside."
(I can't decide, Scissor Sisters)

486 - "It's the final pants!"
(Final Countdown, Europe)

487 - "Tommy get your pants down here!"
(Kimberly, Mighty Morphing Power Rangers The Movie)

488 - "It sucks to be pants."
(Zane, Yu-Gi-Oh! GX Abridged)

489 - "PATHETIC PANTS! THERE'S NO ESCAPE!"
(Starscream, The Transformers The Movie)

490 - "Let me guess you don't want pants either."
(Rarity, MLP FiM "Suited For Sucess")

Here are the last ones:

491 - "I can't exactly smile in pants mode can I?"
(Ratchet, Transformers Animated "Garbage in Garbage Out")

492 - "Card games on pants!"
(Jack Atlas, Yu-Gi-Oh! Abridged "Card Games On Mototcycles")

493 - "From Russia with pants."
(From Russia with Love, Matt Monro)

494 - "One life for yourself and one for your pants."
(You Only Live Twice, Nancy Sintra)

495 - "And I'll bet you think these pants are about you."
(You're so Vain, Carly Simon)

496 - "Crash Bandicoot for the last time, give the pants to me."
(Uku-Uku, Crash Bandicoot Warped)

497 - "Bandicoot Pants!"
(Coco Bandicoot, Crash Team Racing Random Quote)

498 - "Let me see your war pants!"
(Drill Sergant, Full Metal Jacket)

499 - "Know my pants!"
(Meta Knight, Super Smash Brothers Brawl Final Smash)

And to end it all

500 - "Friendship is Pants."
(MLP FiM Extended Theme Song)

901650

Want to do 1000 pants, now? Or 500 shirts?