1: A group of thugs attack the mane six and Celestia decides they need a body guard. They find a group of humans being trained in martial arts. The master allows them to have one. The human, who is blunt and very protective, wants to live a normal life, but puts his duties first. The mane six try to give him his wish.

2. A bit like Detroit Become Human. The worlds of ponies and humans collide. The humans have enslaved the ponies, turning them into servants and forcing them to do their bidding. A group of human college students discover that they are living beings and that they deserve to be free. With the help of some new friends, they break into the facility keeping them under control but fail. Now they’re all on the run, trying to create a new plan.

3. A human adopted In Equestria story. Possibly a collab?

4: Freddie Mercury in Equestria

5. 2 human kids, a boy and a girl, enter the world of a more realistic equestria. They need all the help they can get!