For me, it's a three-way tie between Arianna, Iosefka, and Adella.

7036037

Hmmmm. . . hard choice, but i guess it would be a split between Annalise, Queen of the Vilebloods and Vileblood Hunter Alfred, ironic huh, but i do love there questline and how it end's with Alfred trying to turn himself into a martyr, thus ending the executioner's faction and leaving you to restore Annalise and the Vileblood's.

Doctor Iosefka (fake) is also a good choice, just because she manages to pull a eviler then though on the Afflicted Beggar.

7036494
Yeah, the thing you said about Iosefka is definitely a plus.