i think one of the biggest cliche aside from manticores and the everfree forest landing,

Is how the ponies always flip their shit when they see a human kill a bad guy,despite the fact that the said bad guy wants them dead. I mean show some goddamn gratitude.

Another one that needs to go is how the ponies are horrified with the idea of humans eating animal meat. And fluttershy shouldn't freak out,consdering that in one episode she was feeding a ferret fish.

And let's not forget about how the human accepts that he's in a world not of his. While in real life the said human mc would have a mental breakdown.

Instant romance
"Hey I'm human, let's bang"

Misanthropy
"HUMANS BE THE EVIL DOERS!!!!!!" "I'M A GOOD ONE THOUGH!"

There are plenty of others but I'll let other people contribute to this.