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Ambien is a prescription medication primarily used to treat insomnia, a sleep disorder characterized by difficulty falling asleep, staying asleep, or both. The generic name for Ambien is zolpidem. Ambien is a sedative-hypnotic medication that works by affecting certain chemicals in the brain, including gamma-aminobutyric acid (GABA). GABA is a neurotransmitter that helps regulate sleep by slowing down brain activity. Ambien enhances the effects of GABA, which helps induce sleep and promote relaxation.