I'm making this thread so people (or ponies, depending on who you are) can post good seeds they've found for TBoI: Rebirth, or ones that are just interesting. Note that all the seeds I post will be for PC.
Here's a seed I discovered that starts you out with Fire Mind, then it ends up giving Spoon Bender in the next Treasure Room, followed by Dead Onion in the Caves. It all turns out into a high damage loadout, with homing fire tears that pass through blocks. The only downside is that the Dead Onion severely reduces your range. Here you go: PQE3 HHXX

Found an insane run with Judas. This one is all about damage boosts, giving you Polyphemus, followed by... God, I don't even remember. Your damage goes off the charts, and if you play it right you can snag Hive Mind in a shop then grab the Mulligan in the boss rush. Here's the seed: GHBS TVFZ