Harriet Bree(?): *in a demonic, warped voice* "General James Ironwood... we meet at last."

Ironwood: "Why do you want the Staff of Creation?"

Harriet(?): "My goals are beyond your understanding."

Ironwood: "Hmm. I wouldn't be too sure of that. I was able to capture you, after all... I must say, your Semblance and even your very appearance are almost exactly like those of one of our Ace Operatives. Tell me, does a Miss Harriet Bree mean anything to you?"

Harriet(?): *laughs* "Oh, I'm not like Harriet Bree at all... some would say I'm the Reverse."

Artwork courtesy of this guy.

7121821
Is that a reference to the flash

7121896
Well, considering that Harriet's Semblance pretty much looks exactly like the Flash's Super-Speed when he runs, I'd have to say yes. Or more specifically, it's a reference to...

7121900
Neat