It's over. She's been with Celestia for years. She's absolved Luna of her crimes. She's been instrumental in defeating Sombra, and has revealed a Changeling invasion. She's even helped in reforming Discord. And now, her time is over. In the time that she's had, she's tried to do her best. She's tried so hard to live up to what other ponies expect of her.

And they were happy with how she was shaping up.

They wanted her to succeed.

Now all they want is to see her dead.

Story has been pre-read or otherwise edited by these fantastic ponies people:
Blood Lord
Ecstatic
seeker9709
PsyonicG

When Twilight Sparkle slipped beneath the covers last night, everything had been fine. She had friends whom she loved, a teacher she adored, and a bright future ahead of her. But when she woke up, her blankets and quilts had been replaced by hospital gowns and padded restraints.

Everything is wrong and nothing makes sense; even her friends have changed. The doctors keep telling her that she is sick, that none of it was real and that it was all in her head. Yet she remembers a life far beyond the hospital walls. She couldn't have made it all up on her own. They must be lying… right?

Ask Asylum Twilight - Still updating regularly!
Equestria Daily
TVTropes
Asylum Fan Group
The Tartarus Project
Russian Translation
The Asylum 20,000 View Spectacular Stage Show!

Art:
Asylum Cover by conicer
Twilight and Twilight Smiles by dreamingnoctis
Mirror Twilight and Plague Doctor by Jaestring / BloodGoldWings
Twilight Smiles and Doctor AJ by conicer
Nurse Ratchet and Silas and What's in the mirror? by Archonix
Doctor AJ Sketch by Archonix | Colored and vectored version by ReFro82
Twilight's Asylum by Khan the Cake Lover
Smilight by HappySwitch
Twilight Waking Up by Dombrus
Fan Art by toxicdemon10
Asylum Twilight by Madness-With-Reason
Asylum Fluttershy and Asylum Ch 26 by Downburst-Backspace
Twilight and her Twin by v747
Birdgirl by sirValter

Readings and Videos:
Asylum Animated Trailer Video by formuladash
Reading by Gammarobot (SugarCubeRadio): All Chapters Here
Reading by Ender Brony: All Chapters Here
Reading by VisualPony: All Chapters Here
Reading by MelancholyIguana: All Chapters Here
Fan Trailer by Kaidan: Asylum FanFic Trailer Cuckoo's Nest

Sanctuary by Kaidan
Broadhoof Files: Dr. Humors by TypewriterError
Broadhoof Files: Corporal Phalanx Spear (Ret.) by Phalanx Spear
A Hearth's Warming Tragedy by Seven Fates

A special thanks to Breath of Plagues, Rex Ivan,
ChudoJogurt, Cynewulf, Death the Kid, Selbi, PrinceDolph, Blahman2816, Queue, and Gage!

Axan Zenith - Dr. Dreamer
Dratini4 - Way Finder
psychicscubadiver - Bright Mind
Velkaden - Dream Chaser
Reese - Silver Glow
Viola Heartstrings - Clover
Archonix - Spinney Whiteacre

There has always been a little voice in Twilight Sparkle's head, whispering dark musings to her. And until her brother's wedding, she has managed to push those bitter thoughts away and focus on the good. She forgives and forgets and holds onto hope.

But when her friends turn their backs on her and her brother cuts her from his life, Twilight finds herself alone, with only the little voice to comfort her.

And it is through anger and hate that has been repressed for so long that Twilight finds the power to rise up. Harmony and Friendship have only brought her pain and suffering. It is time for her to embrace her dark side. No longer will she worry about what others think. Twilight is going to live her life how SHE chooses: without friends, without family, without love and without harmony. She is going to cut loose, have fun, and screw what others think.

For her friends and family, it will soon become apparent that if they don't find a way to mend the damage they've done to the lavender mare...Twilight Sparkle might be lost to them forever.

Thank you to everyone that got this story as one of the Featured Stories here on the site!

The TvTropes Page can be found here: http://tvtropes.org/pmwiki/pmwiki.php/FanFic/FaithAndDoubt

Cover created by the amazing FerGarcia220

Celestia had a problem. Somepony wrote a novel about Nightmare Moon's rebellion. This made Luna quite unhappy, and unfortunately for her sister, Luna has not yet gotten the hang of modern traditions like freedom of speech, the abolition of the death penalty, and not bothering Princess Celestia when she's trying to sleep.

Fortunately, Celestia also had a faithful student, one who is now a Princess with an ill-defined portfolio and perfectly capable of dispensing justice by the laws of both today and one thousand years ago.

Now Twilight Sparkle has a problem.

(Title image hacked together from vectors by Martinnus1, Hawk9mm, and Paulie15.)

When all hope seemed lost, six ponies came together to form an unbreakable bond. In one swift stroke, the magic of friendship defeated Nightmare Moon and saved Princess Luna from the shadows...

But still the night remained.

A collaborative work with the immeasurable Eakin.

This story is a sequel to The Traveling Tutor and the Diplomats Daughter

“You should have burned their aerie to the ground two centuries ago and killed every one of them when you had a chance, Tia.”

These words trigger a series of events that send four ponies to the far northern Misty Mountain Aerie where Wingmaster Talon is threatening to invade the newly discovered Crystal Empire. The Diplomat, Luna's Hoofmaiden, and two Royal Guards are to face hostile griffons and dangerous mountains in order to bring peace to the region and prevent a war.

But what they find in the mountains is far worse than they could imagine, and their only chance for survival becomes a race to escape in a battle to the death.

Featured on Equestria Daily [Adventure][Sad]

Written to stand alone, but follows :
The Traveling Tutor and the Diplomat’s Daughter
Diplomatic Security
Genealogy (or the mating habits of Nocturnes Pegasi)
To Sleep, Perchance to Dream

Editing assistance provided by Peter and Tek.

Original line drawing by Ralph Hayes Jr.
Background Summer Campfire by BonesWolbach
Colors and shading by Shaleclaw
Special mention to JoyfulJ for shading on Pumpernickel’s armor.

This story is a sequel to Petriculture

It's been several months since Pinkie Pie made a stunning admission about her past that permanently changed her relationship with her friends, particularly Twilight Sparkle, but life seems to have settled back to normal (well, normal by Pinkie Pie's standards, at least). However, when an old nemesis returns and ensnares Twilight in her influence, it's up to Pinkie to make things right.

This is the second story in The Petriculture Cycle. There is a TV Tropes Page for the entire Cycle here.

Cover image by Page Turner; "Princess Twilight" vector by Nianara.

This story is a sequel to A Song of Storms: Of Skies Long Forgotten

It has been twenty years since the fall of the Cirran Empire, and Commander Hurricane has led the pegasus pony tribe into a comfortable role in accordance with the Tri-Pony Compact. But a supernatural blizzard without end brings forth the suppressed hatreds that have festered among the three tribes, and the resulting famine threatens to eradicate all; earth pony, unicorn, and pegasus alike. With a bloody war looming on the horizon and the fate of their ponies at stake, the three tribes must find a way to survive together, or they will assuredly die alone.

Sequel to "Of Skies Long Forgotten." Reading of that story is not absolutely necessary to understand what is going on, but it is strongly recommended for you to understand the references.

Officially part of "The Price of Loyalty" storyverse, in collaboration with LoyalLiar

Editing by LoyalLiar and Ruirik
Cover art provided by Ruirik

This story is a sequel to The Promise of a New Day

Story three of Savage Skies:
All sorts of things are brewing in the pegasus city of Cloudsdale, which is a problem for Ponyville as the one thing that isn't is a rainstorm. As the drought continues to drag on, Rainbow Dash must confront her hometown and its history, as well as her own history. But she won't do it alone, which is good, because she'll need all the help she can get.

Series starts with Foal of the Forest.
Now with a TV Tropes page.

When Discord hears that his botanical creation, poison joke, continues to flourish in the Everfree, he simply cannot resist a good prank. Poison joke in hand, he storms Canterlot Castle.

Needless to say, the princesses are not impressed. But then, neither is Discord, since the joke also has an unexpected effect on him. And none of them know the cure.