Given a multiverse full of infinite possible realities, it stands to reason that at least one version of Twilight Sparkle would end up as a magical anthro-cat schoolgirl ninja. That's just *physics*, y'all.
Twilight Sparkle inadvertently causes an inter-dimensional royal incident. Rarity and Applejack spend the day together. Rainbow Dash makes a new friend. Sweetie Belle drinks tea. The world ends.
Celestia has plunged the World into eternal daylight. Luna is defeated, the Crystal Empire trapped, and communication impossible. So clearly, the Cutie Map calls Twilight and her friends to solve the problem. Its priorities turn out to be debatable.
Trixie's wagon wheel breaks, stranding her in the middle of Hoofington. Unable to fix it herself, she must call upon Equestrian Roadside Assistance for help. If help will ever come, that is. Which it probably won't.
When one of the Elder Gods is unwittingly summoned to the mortal plane, it's up to Trixie, Rainbow Dash, and a gallon of milk to save the day and send the beast back from whence it came.
Heady adventurous exploits? Ridiculous romps and hijinks? Feeble attempts at 19th century writing styles? Sounds like an adventure befitting the intrepid Pinkamina Pie! Who let Pinkie get her hooves on a hot air balloon anyway?
When Books all over Equestria vanish, there is only one thing to do! No, not having the Princesses or guards or police actually do their job, no. It's time for the Mane Six to kick some butt again! Or...is it?