I'm not really sure what to say, so... quoting Wanderer D's signal boost:

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In short: a needed surgery that is expected to probably go fine, but best case scenario still have a painful recovery. They're looking for some help getting a comforting Starlight Glimmer plushie, and could likely do with some general encouragement.
(I got to this a bit late, late enough, it looks like, that when I in the process of composing this blog post checked for additional details, I discovered that the plushie had already been fully funded. :))

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This time, a colleague of Dreams of Ponies, who has a blog post about it here with more details and a donation link. In short, though, she was badly injured in an automobile accident and could use some help.

...Well.
GroaningGreyAgony's mother has passed
...I don't appear to have had the best timing with that signal boost.

They're still making the trip down, though. ...Less of a hurry, now. But still things to take care of.
So... yeah.
Again, probably you should check the Estee blog post linked above for more information.

In terms of physical needs, as far as I know, he's pretty much fine. Could do with some travel money, with a PayPal link in the blog post I'll be linking to in a bit, but he sounds like he's got enough for the immediate future, at least.
Unfortunately, said travel money is to go and see his almost-certainly-dying mother... or at least try to, before the trip suddenly gets less urgent for unhappy reasons.

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A donation system is now available, as detailed by Trick Question here:

Fortunately, he is now able to take donations if you have a Paypal account by sending them directly to his email address, prayforkarltowns at outlook dot com. If you can send anything his way—even just a couple of bucks—it'd be appreciated.

The blog post is here, but quoth a comment on it with more information:

Things are bad at the moment; we are in the red and don't yet have solid prospects for getting out. The temporary fix I mentioned is looking shakier than I thought and we're having to seek cheaper housing.

Without meaning to be grim, anything you can do would be wonderful

They're having some financial trouble, with more details over here.

He's hit some financial difficulties and is both accepting donations and offering more commissions than usual; details over here.

The full blog post is rather long, which seemed to me like it might put some people off and/or be too much for the time they had available, so I picked out a couple of paragraphs that I thought summarized the financial need well enough:

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