Sweetie Belle magically derails a science experiment, causing her to switch bodies with Rainbow Dash. They try to masquerade as each other, but the weather team needs help and Diamond Tiara, well, is Diamond Tiara.
After the collapse of a high-rise during the events of "The Mysterious Mare Do Well," Twilight decides that she needs to bring the Architecture industry into the new millennium.
There are a number of compounds the human body is incapable of synthesizing; these are found only in red meat. To save a dying human, Twilight asks her friends - except for Fluttershy - for advice.