After the monstrous U-3 is defeated by Leon in Spain, it wakes up on the edge of the Everfree forest. But something is different. It has become reacquainted with the sapience it once knew from when it was human. What's more, the mind-controlling plaga is being strangely quiet. Unable to speak and stuck in a horrifying body, can he get anybody to help him figure out what's going on?

This is a crossover with the game Resident Evil 4.