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Disk seems to be the Ember Island Players version of Katara (from Avatar: The Last Airbender) - "A preachy crybaby who can't resist giving over-emotional speeches about hope all the time", and Key seems to come across as somebody more interested in simply breaking Disk, rather than teaching him to survive in the Wasteland.

We'll have to work on that.

Hopefully Disk will get more chance to use his engineering prowess more, since his medical skills have been on display more often so far.

What does the disease in Vault 25 actually do? Is it just like Rustlung, or has it got specific symptoms?

These will be addressed in the future.

How did Solaris stay in business if their products were on record as being so bad? Even in a free economy (and I see Equestria as being more subsidised), they couldn't slash prices enough to undercut proven producers like Stable-Tec.

Yes, strange isn't it?

What is the age difference between Disk and Key, and Disk and Barrel?

I hate to put definite ages on ponies, but I imagine Disk and Barrel being similar ages, and Key being slightly older than the both of them.