What scenarios could you come up with? So we got super op, godlike ponies that could wipe out the entire human race with ease. Their bodies are basically indestructible from anything we can use against them.

They could perhaps even be robot ponies, but instead of magic, they use technology to help you. Even the robot ponies could simply turn into grey goo and simply eat Earth if they wanted to. But don't since they don't like killing meatbags.

Yet, all these ponies (robots or not) really want is friendship... and even romance with humans. And show that someone cares about them in the dark void of the universe. How would humans react to such gentle, but godlike beings?

I´ve been thinking about that for a long time, but in my version, they are not directly godlike, they are just stronger, faster, bigger and more durable than humans. Like technically, humans COULD win against them, if they have the advantage in numbers, a good strategy, and get lucky.