Spike leaves behind his life in Ponyville, maybe he returns and maybe he doesn't. Wherever he ends up, he learns to call the place home.

-Banished/Exiled for something out of his control, such as his instincts or being framed for a crime he didn't commit.

-Freedom from being the servant/slave/lapdog of Twilight and the Mane Six.

-Discovery of who he is as a dragon.