Midnight Sparkle controlling the human world or Equestria is a theme that has so much potential. Here are some fanfictions with this theme: https://www.fimfiction.net/story/336215/the-empresses and https://www.fimfiction.net/story/472243/the-me-in-the-mirror-the-me-in-dreams

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Why not? Technically Midnight is an evil Twilight, she's just the evil alter ego of Sci-Twi rather than the Book Horse.

No.