The Rogues-Flash's enemy organization-suddenly wakes up ponyfied in the magical land of Equestria, and everything just goes downhill from there, as they, and every citizen of Equestria, works desperately to get snarky, drunk, blue-collar supervillans back home, before all of Equestria is destroyed...because none of them want to put up with rainbow horses anymore. Well, maybe Trickster, but he was always insane anyway.

"[The hunters' thoughts were] crowded with memories...of the knowledge... that they had outwitted a living thing, imposed their will upon it, taken away its life like a long satisfying drink." Chapter 4, pp. 63-4 (Lord of the Flies)
After years of darkness growing in her heart, Ditzy Doo has become corrupted. Taking the form of the Shadow Queen, she now rules Equestria in darkness as the most powerful force anypony has ever seen. The only hope lies in Harmony, but with the Mane Six having disappeared, it will be harder than ever before to return the Light to Equestria.