(Indirect sequel to "The Power Ponies: Birth of a Mane-iac". Familiarity with that fic is encouraged but not necessary.)
Hum-Drum and The Power Ponies are shocked to be contacted by their arch enemy: The Mane-Iac. And she isn't looking for a fight, not this time. No, The Mane-Iac claims she's really sick, to the point where she's dying.
However, The Mane-Iac has one last trick up her sleeves. She's got a special spray ready to be released on an unsuspecting Maretropolis upon her death. And the only way she can be cured is with a special beauty product that's being delivered to Maretropolis' dock yards.
But The Mane-Iac is unusually specific in wanting Hum-Drum to go alone to retrieve what she needs, threatening to prematurely unleash her spray if The Power Ponies interfere. Hum-Drum reluctantly accepts, not anticipating what the real reason for him being chosen is.
Love the Crash Bandicoot reference.
This is another good story, and I can certainly see a few references to Joker's situation in Arkham City here. Though, if this is a sequel to "The Power Ponies: Birth of a Mane-iac", then I am a little surprised that there was no comment on her and Hum-Drum's past together, especially since she was a love interest for him before her transformation there. I would of thought if she was spending her last moments with him she might have wanted to try to rekindle their old love, maybe even share a "final goodbye kiss", but there was very little romance mentioned between them. So it didn't feel much like a "sequel", indirect or otherwise, just a stand alone story.