Fluttershy has tried being patient and she's tried the cute routine. But a mare has needs. She wants in your pants. And pony logic dictates that finding your fetish is the way to do it.
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What the fuck, Fluttershy?
How do you just put aids on a toilet seat!
6838583 Methodically.
I don't comprehend this.
6838583 Meticulously
6838583 Well, you'd need to grow the virus to a high titer - probably higher than you would find even in the blood of an end-stage, viremic subject. You might be able to achieve a high titer by culturing the cells in HEK 293T cells (that works for lentiviral vectors, so it ought to work for AIDS itself), but of course ponies aren't going to have that. They might have some other kind of immortalized cell line that they could use.
Once you have a lot of virus made, you'll need to spin it down in an ultracentrifuge, taking care to use an appropriate medium to preserve viability. Spin-downs are not gentle on the virus. Remove the supernatant and replace with medium of your choosing. I would recommend a medium rich in trehalose - that will stabilize the virus when you apply it to the toilet seat. You might also mix the medium with small, porous silica granules to facilitate passage of the virus through the epidermis, although that last component is just armchair speculation on my part.
6839547 You spent waaaay too much time on that response. Go find a cure for cancer with those smarts.
the last chapter gave me feels
then this chapter got me like WTF??
Well, at least he'll have an interesting story to tell the repairpony, plumber and doctor today.
This reminds me of... nevermind.
Hoh, fuck, that was good.
Well... Uhhh... There's a fetish for everything, I guess...
God dammit, i thought there would be a plot! oh well this is what i originally came for anyway!
I'M SO CONFUSED!
Well, as much as those horrified me, I've got to give her points for originality.
6839547 Regardless of how much work you put into the virus creation, if the victim doesn't have an open sore or open wound on their backside, in direct contact with the seat, I don't see how it's getting into the body in the first place.
Oooooooh lordy... Fluttershy.... hahaha XD
6839547 Your avatar makes more sense now...
Wait how did her get pony aids by shitting???
7596118
True One: Two words, Anal Mucous.
Real One: Translating, you rear exit.
Hells Fire: You two are disgusting.
but whyyyyyy
Hey she finally did it! :D
7546088 and you're avatar nearly made my heart stop.
...But He didn't stop to use the bathroom. How'd He get AIDS?
7929967
he shitted but then made breakfast
The pool has AIDS
im so confused
Well, if you've been wrong so many times, eventually you think of the most batshit crazy solutions possible.
you should have put sleeping meds in his food supply, then when he's asleep, ya know. Hot dog to donut😈
My place. Five minutes. Next chapter : Pony AIDS
But can pony AIDS infect a human?
9380510
I agree. Where the follow-up from the last chapter? I thought they were getting together to plow each other until the place is overrun with their children and this nightmare would have been over forever. Also Fluttershy, how the heck will giving someone AIDS make them want to have sex with anyone/anypony and spread it all over the place? Finally how will injuring or killing Aron make him be able to have sex with anyone/anypony? Think God damnit.