I will way thinking about this question and how everyone will react.
1) How will Ponyvill react? thnk Ponyvill be vary glomy for like five years or so.
2) How will Twilight, Dash, Flutershy, AJ,and Rarity react? i think it might damge thier mental state.

2326778 Your spelling and grammar is damaging my mental state.

2326778
What you are trying to say is would anyone be sad if pinkie and spike died? I think with how Spike and Pinkie are treated by the fandom they wouldnt be missed at all but their friends would surely be devastated that i know.

2326843 you are good at somethings and bad at somethings for me it is grammar, pacing, and spelling.

2326949
I don't agree with that.

2326778 I would say that everyone would be sad about Pinkie while those close to Spike and the Crystal Empire will be sadden by his death.