Lady Layton in Equestria:

In some "future of FiM" (and believe me, there are a number of those ideas), perhaps the Layton Detective Agency (Katrielle Layton, Professor Layton, Earnest Greeves, Sherl the Dog, Luke Triton), and possibly Lucy Baker and Alfendi Layton, might be summoned to Equestria to solve some mystery.

Any ideas what might happen?

I'm particularly hoping someone might speculate or offer suggestions or even write a fan fiction.